EFFECTS OF THE AURORA KINASE INHIBITORS AZD1152-HQPA AND ZM447439 ON GROWTH ARREST AND POLYPLOIDY IN ACUTE MYELOID LEUKEMIA CELL LINES AND PRIMARY BLASTS

Background Aurora kinases play an essential role in the orchestration of chromosome separation and cytokinesis during mitosis.Small-molecule inhibition of the aurora kinases has been shown to result in inhibition of cell division, phosphorylation of histone H3 and the induction of apoptosis in a number of cell systems.These characteristics have led

The article is concerned with energy conservation in the process of cleaning grain.The study aimed to find ways of reducing energy consumption when cleaning food grains by using energy-saving operating modes (ESOM) on the production lines of grain storage facilities.For this purpose, experimental tests were performed which involved studying the eff

Khaled M Hosny1,2 1Department of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Saudi Arabia; Spinning Top 2Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, EgyptCorrespondence: Khaled M HosnyDepartment of Pharmaceutics, Faculty of Pharmacy, King Abdulaziz University,

Abstract Fairness in policing, driven by the effective and transparent investigation and remediation of police misconduct, is vital to maintaining the legitimacy of policing agencies, and the capacity for police to function within society.Research into police misconduct in Australia has traditionally been performed on an ad-hoc basis, with limited